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Prussian Blue Nanoparticles for Targeting Cancer Cells
Immune checkpoint inhibitors have shown promise in cancer treatment by helping the immune system recognize and attack cancer cells. However, many tumors remain resistant to these treatments. To address this challenge, Dr. Rohan Fernandes, a professor at George Washington University, developed a novel patented technology by combining Prussian Blue Nanoparticles...
Published: 2/18/2025
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Inventor(s): Rohan Fernandes, Preethi Balakrishnan, Jacob Medina, Elizabeth Sweeney
Keywords(s):
Category(s): Technology Classifications > Therapeutics > Nanoparticles
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Engineered Nanoparticles Improve Immune Response to Photothermal Therapy for Cancer
Neuroblastoma is a severe form of cancer and accounts for 15% of all cancer related deaths among children. However, the current modalities of treating this cancer have limited efficacy and are deficient in preventing recurrence. This can be attributed to the heterogeneous and immunosuppressive nature of the cancer coupled with low neoantigen expression.
Researchers...
Published: 2/18/2025
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Inventor(s): Rohan Fernandes, Elizabeth Sweeney, Juliana Cano-Mejia
Keywords(s):
Category(s): Technology Classifications > Therapeutics > Nanoparticles
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T cells targeted against multiple antigens for cancer treatment
GW researchers developed a cell therapy platform to manufacture multi-antigen-specific immune cell products for treating cancer. Tumors often are sheltered from attack by a patient's immune system. One problem is immune cells at the tumor may be dysfunctional, so they are unable to recognize and eliminate the tumor cells. Current gold-standard cellular...
Published: 2/18/2025
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Inventor(s): Elizabeth Sweeney, Rohan Fernandes, Conrad Cruz, Palak Sekhri, Preethi Balakrishnan, Matthew Tovar
Keywords(s):
Category(s): Technology Classifications > Therapeutics > Cells
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PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 2/18/2025
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Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
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