|
3D Printed Biomimetic Blood Vessels
Efforts to develop small-diameter blood vessel grafts for biomedical use have faced significant challenges due to the limited availability of vascular autografts and artificial alternatives. Traditional materials like polylactic acid (PLA), commonly used in 3D printing, lack the required flexibility and porosity to support efficient blood flow and nutrient...
Published: 2/18/2025
|
Inventor(s): Sung Yun Hann, Haitao Cui, Lijie Zhang
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Regenerative Medicine
|
|
A novel noninvasive nondestructive means to measure viscosity of biomaterials for biomedical applications
Hydrogels are pivotal in the realm of biomedical applications making them ideal for tissue engineering, drug delivery, and wound healing. Traditional methods for assessing the viscoelastic properties of hydrogels, such as shear rheology and compression testing, while standard, present several drawbacks. These include sensitivity to experimental conditions,...
Published: 4/14/2025
|
Inventor(s): Kausik Sarkar, Megan Anderson, Lijie Zhang, Kartik Bulusu, Michael Plesniak
Keywords(s):
Category(s): Technology Classifications, Technology Classifications > Medical Devices
|
|
Self-morphing 4D-printed programmable culture substrate for controlling neural stem cell growth
Neural stem cells (NSCs) exhibit great promise for treating neurodegenerative diseases and injuries. Treatments will rely on efficient proliferation and differentiation of NSCs into neurons with therapeutic characteristics. Static 2D and 3D microenvironment culture substrates fail to cater to the dynamic cell needs, resulting in sub-optimal, inefficient...
Published: 2/18/2025
|
Inventor(s): Shida Miao, Haitao Cui, Lijie Zhang
Keywords(s):
Category(s): Technology Classifications > Research Tools > Buffers and Media
|
|
PMU-Embedded Analytics for Online Event Detection and Classification in Power Grids
The energy requirement of the world is increasing exponentially every year. With the power demand sites concentrated in the region with the highest population density, energy production sites must be located remotely. This isolation requires lengthy and complicated grids to be designed and manufactured to transmit power over long distances. Grid failures...
Published: 2/18/2025
|
Inventor(s): Payman Dehghanian, Shiyuan Wang, Li Li
Keywords(s):
Category(s): Technology Classifications > Industrial or Consumer Tech > Energy Infrastructure and Environment
|
|
Thick 3D Bioprinted Cardiac Patch with Anisotropic and Perfusable Vessels
GW researchers fabricated a vascularized patch of cardiac tissue suitable for cardiac regeneration using 3D bioprinting. Cardiovascular disease involving myocardial infarction is a major cause of morbidity and mortality worldwide. Following myocardial infarction, adult cardiac tissue cannot significantly repair or regenerate itself. Current therapies...
Published: 2/18/2025
|
Inventor(s): Lijie Zhang, Haitao Cui, Yimin Huang
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Cardiology
|
|
Vascularized bone construct using dual 3D bio-printing & regional bioactive factors
GW researchers generated a vascularized and highly osteogenic bone construct with a biphasic structure using a multiple 3D printing platform. Traditional tissue engineering techniques face major obstacles in creating multiple tissue structures and vascularization of tissues. 3D bioprinting allows for control over the location of cells and biomaterials;...
Published: 2/18/2025
|
Inventor(s): Haitao Cui, Wei Zhu, Lijie Zhang
Keywords(s):
Category(s): Technology Classifications > Medical Devices > Regenerative Medicine
|
|
3D printed vascularized tissue scaffold with extracellular matrix triggered growth factor release
Vas-Scaf” is a 3D bio-printed vascularized bone scaffold perfused with osteogenic and angiogenic growth factors. Artificial bone grafts lacking vascularization fail due to poor integration of new tissues with the host and death of interior bone tissues. Bone and blood vessel tissues require different support structures and different biochemical...
Published: 2/18/2025
|
Inventor(s): Haitao Cui, Wei Zhu, Benjamin Holmes, Lijie Zhang
Keywords(s):
Category(s): Technology Classifications > Therapeutics, Technology Classifications > Therapeutics > Nanoparticles, Technology Classifications > Industrial or Consumer Tech > Materials
|
|
3D Shape Memory Scaffolds for Tissue Engineering
Over 120,000 patients are currently waiting for lifesaving organ and tissue transplants. Tissue engineering has the potential to innovate transplant and minimally invasive surgery by creating tissue substitutes from biopolymers with human stem cells.
GW researchers developed a plant oil infused biopolymer with unique characteristics that are highly...
Published: 2/18/2025
|
Inventor(s): Shida Miao, Wei Zhu, Nathan Castro, Lijie Zhang
Keywords(s):
Category(s): Technology Classifications > Industrial or Consumer Tech > Materials, Technology Classifications > Therapeutics > Cells, Technology Classifications > Therapeutics > Small Molecules
|
