Researchers at GW have developed a system that can effectively and accurately allow a respective practitioner to place a “His Bundle Pacing” electrode on a subject’s heart as part of various known cardiovascular procedures. In particular, the system can include a bioelectronic catheter having at least one multilayer electronic array that can allow multiplexed sensing and actuation of various cardio-vessels during various cardiovascular procedures. In an embodiment of the invention, the system effectively prevents the damage of “His Bundle Pacing” electrode during placement on a subject’s heart that has hitherto been unaddressed in the art. Further, the system can effectively process various parameters that a practitioner requires, in a respective cardiovascular surgery, by way of multiplexed multimodal soft bioelectronic arrays that can allow mapping of respective temperatures, pressures, and other electrophysiological parameters as can be appreciated.
The disclosed invention can be implemented as either a system, a method, or a device as can be appreciated. The system, method, or device can include various aspects as follows: (i) at least one multiplexed multimodal soft bioelectronic array that can allow mapping of respective temperatures, pressures, and other electrophysiological parameters; (ii) instrumented sensors and actuators in multiplexed array formats, with spatial densities designed to probe the complex nature of tissues, specifically the heart; (iii) multilayer architectures with combined diagnostic and therapeutic functions, including the latest cardiac procedures that rely on electroporation. In one embodiment, the system, method, or device can include arrays of electrodes, temperature sensors, pressure sensors in single nodes of a multilayer mesh.

Fig. 1 – One example of the disclosed “His Bundle Pacing” electrode for use in the disclosed method, system, or device
Applications:
- Allows better clinical management of cardiac desynchrony by overcoming limitations in the biological understanding of “His Bundle” conduction properties including longitudinal dissociation
- Implementation in various cardiovascular medical devices such as catheters and others as can be appreciated including minimally invasive surgical devices
Advantages:
- Allows for accurate placement of “His Bundle Pacing” electrode on a subject’s heart
- Prevents damage of “His Bundle Pacing” electrode during placement on a subject’s heart
- Allows for mechanical rigidity of an underlying medical device