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Intranasal leptin to treat opioid-induced respiratory depression (OIRD) in obese patients
Respiratory depression is the leading cause of morbidity and mortality associated with opioids. Patients with obesity experience pain and need opioids more frequently than normal-weight individuals. Chronic consumption of opioids is associated with addiction, physical dependence, and tolerance. Tolerance leads to requirement of higher doses of opioids...
Published: 2/18/2025
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Inventor(s): David Mendelowitz, Vsevolod Polotsky, Carla Freire
Keywords(s):
Category(s): Technology Classifications > Therapeutics
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