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(Technology Bundle) Stem cells with transiently reduced p53 to treat diabetes associated kidney disease and peripheral vascular disease

Local delivery of endothelial progenitor cells (EPCs) may treat diabetic-related kidney disease (DKD) and peripheral vascular disease (PVD). EPCs may be obtained from a patient’s peripheral blood. The hyperglycemic state in diabetic patients causes transplanted EPCs to undergo apoptosis, creating a challenge for such therapies. By transiently...

Published: 6/17/2026 | Inventor(s): Sabyasachi Sen

Keywords(s):

Category(s): Technology Classifications > Therapeutics > Cells

(Technology Bundle) Stem cells with transiently reduced p53 to treat diabetes associated kidney disease and peripheral vascular disease

Published: 6/17/2026 | Inventor(s): Sabyasachi Sen

Keywords(s):

Category(s): Technology Classifications > Therapeutics > Cells

Cell‑Free Exosome Therapy to Rebuild Kidney Function in Diabetes

Chronic kidney disease (CKD), particularly in patients with diabetes, represents a large and growing unmet medical need, affecting tens of millions of people worldwide and leading to progressive loss of kidney function, cardiovascular complications, and high mortality. In diabetic CKD, persistent high blood sugar damages the endothelial cells that line...

Published: 6/17/2026 | Inventor(s): Sabyasachi Sen

Keywords(s):

Category(s): Technology Classifications > Therapeutics > Proteins and Peptides